Adipex vs Duromine: Which is better?

Teresa Hong

Teresa Hong


Teresa Hong is a dietician who is actively engaged in food education. Develops nutritional methods available to as many people as possible. Offers specific dietary modification tools for people with endocrine disorders, food allergies, atherosclerosis, malnutrition, irritable bowel syndrome and other diseases. She will help to get rid of stress and enjoy every meal again!

, reviewed by
– Updated November 16, 2021

Duromine and Adipex are two trade names of the same well-known drug Phentermine, which has been approved for the treatment of obesity. Both drugs suppress appetite and are used to treat obesity along with diet and physical activity. Let’s figure out their differences.

Similarities and differences of Duromine vs Adipex

Duromine first appeared on the Australian market in 1991 and gained high popularity as an effective slimming aid. It is natural that rogue manufacturers keep trying to flood the market with counterfeit products and earn money. Therefore, it is highly recommended to buy the drug only from trusted sellers.

In US pharmacies, Adipex appeared in 1980 in tablets. The production of 37.5 mg Adipex capsules began in 1983.

Even though these weight loss drugs provide the same therapeutic effect, they have several differences, such as:

pharmaceutical form;
the duration of the therapeutic effect;
indications for use;
the dosage of Phentermine in each of these diet pills.

Pharmaceutical form capsules of 15 mg, 30 mg, and 40 mg of phentermine in the form of an ion-exchange resin complex capsules of 37,5 mg phentermine hydrochloride (equal to 30 mg of phentermine base) 
Time of action
the active ingredient is released within 10-14 hours
anorexigenic effect – 25 hours
the maximum concentration of the active substance is achieved in 3-4 hours.
an anorexigenic effect – 8 to 10 hours.
Indications for children over 12 and adults under 64 y.o.
with risk factors (diabetes mellitus, dyslipidemia) in BMI 25 and above
over 16 y.o. with BMI 27 and above.

In medical practice, Adipex tablets or capsules can easily replace Duromine. If a person has been prescribed Duromine 30 mg, he can replace it with Adipex 37.5 mg capsules or tablets (equivalent to 30 mg of phentermine base).

Which one is better?

Everyone would like to choose the best, right? Both drugs basically contain one active ingredient – phentermine, and if it happens you are resistant to Duromine, you can go to Adipex and vice versa.

Let’s not forget about the apparent advantages of Duromine:

A longer time of action of the active substances;
Usage in diabetes mellitus and BMI of 25;
Obesity treatment in children and adolescents older than 12 years of age.

Whichever you choose: Adipex or Duromine – the tablets should become a part of your comprehensive weight loss plan; the main points will be a balanced healthy diet and physical activity. Adipex and Duromine ideally help lose weight and increase the effectiveness of weight loss programs. So let’s get to work!


Adipex and Duromine, both containing the active ingredient phentermine, are widely used for short-term weight management in conjunction with lifestyle modifications. While their efficacy is similar, differences lie primarily in their availability, dosages, and legal status across countries. Therefore, the choice between Adipex and Duromine depends on individual medical conditions, personal preference, and local regulations. Always consult with a healthcare professional to determine the most appropriate option for your weight loss journey.


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