Duromine Side Effects: All You Need to Know

Ellen Moran

Ellen Moran


Ellen Moran is an accredited dietitian practitioner on various issues who helps make the basics of nutrition simple and accessible to all. She offers us behavioural changes and specific advice to lead healthy lives and care for our health based on recent scientific advances. She believes and argues scientifically that a healthy lifestyle extends life and makes us happier.

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– Updated January 14, 2022

Duromine is an effective medicine for weight loss in obese or overweight patients. However, like any other medication, its use may cause side effects. These may differ in severity and duration. The below article addresses questions about Duromine diet pills: side effects of short and long-term duration, which include mild, moderate, and severe adverse reactions.

Most frequent side effects of Duromine

Duromine is potent medicine, the use of which requires special attention and caution. On the forum, people often discuss the side effects of Duromine 30mg because this dosage is usually prescribed at the beginning of treatment or used as the main one during the entire anti-obesity treatment duration.

Let’s list the common side effects of Duromine:

Dry mouth
Heart palpitations
Digestive problems
Changes in libido
Mood swings
Bad taste in the mouth

Even though all of the listed symptoms are possible, it does not mean that you will have them. Monitor your health and inform your doctor about any warning signs.

Who can take Duromine

Long-term side effects of Duromine

People taking the drug note that there is a link between long-term side effects and the dosage used. For example, the long-term side effects of Duromine 30 mg and 40 mg are observed quite often. If this is the case, it is recommended to reduce the dosage from 30 mg to 15 mg, from 40 mg to 30 mg, or 15 mg.

To minimize the possible Duromine long-term side effects, you can read more about dosage, overdose, and duration of treatment.

Duromine side effects after stopping the treatment

The fear of losing the weight loss result achieved with the drug makes many people wonder whether stopping Duromine leads to side effects. These are possible if you do not adhere to the recommendations, e.g., continuously take medicine for more than three months or spontaneously exceed the dosage. In this case, the rebound effect may occur, which manifests itself as the following:

Stomach issues
Mood swings
Depressed state
Severe psychological disorder
Sleep disturbance
Abdominal pain, etc.

Observe the recommended daily dose and do not extend the recommended three-month period of use. By following these guidelines, you will already minimize the risk of any potential adverse events.

Dangerous side effects of Duromine, possible in both proper use and overdose

Side effects requiring immediate medical attention include the following conditions:

Chest pain (a possible symptom of Duromine heart attack)
Fast or irregular heartbeat
Labored breathing
Dizziness, fainting
Numbness or tingling in the arms or feet
Swelling of the feet or legs
Tremors in the legs, arms, hands, or feet

You may also find it interesting to read a complete guide about Duromine Dosing and Overdosing.

Since there is plenty of information on the Internet about Duromine side effects in Australia, where it is most popular, many people wonder if it is worth starting to take Duromine at all.

The risk of side effects (including Duromine hair loss) is highly dependent on your current health condition, so be sure to consult with your healthcare professional to make such an important decision. And you can visit our Duromine forum to read more about

How to overcome the side effects of Duromine?

Duromine is one of the most popular weight loss drugs with proven efficacy based on decades of successful use of its active ingredient, Phentermine. Nevertheless, in addition to positive effects, there are also negative ones, but you can minimize them:

Take the pill early in the morning.
Drink as much water as possible per day (about 3 liters).
In some cases, taking the drug every other day may help.
Pay attention to how you feel: if you experience long-lasting discomfort, switch to a lower dosage.
Consult with your doctor.

People who already use Duromine fight unwanted symptoms in different ways. To get more information about such practices, read our forum.

Dry mouth

Duromine and dry mouth (Xerostomia)

The side effects of Duromine vary, but dry mouth is the most common adverse reaction according to numerous surveys of drug users. This condition may last only a couple of days/weeks or until the end of the course or never happen to you.

With Duromine, dry mouth can be a problem and lead to tongue swelling and bad breath. Possible solutions include drinking more water, rinsing your mouth with water, adding saliva-stimulating foods to your diet, and using special moisturizing mouth sprays.

Duromine and headaches

Headache is another common side effect during obesity treatment and can be of indeterminate duration. As a rule, this symptom occurs in the afternoon and at the beginning of the treatment course. Here are the best solutions against Duromine headache:

Use a pain reliever.
Wait until the pain goes away on its own.
Drink plenty of water, since headache is a common symptom of dehydration.

Attention! Do not choose pain relievers on your own. Duromine has a long list of dangerous drug interactions. Talk to your pharmacist or doctor before taking any medicine.

You can also find recommendations from real people who had headaches and successfully managed these while taking Duromine on our forum.

Duromine and high blood pressure

It is known that high blood pressure increases with increased body mass index (BMI). Numerous studies have shown that weight loss caused by calorie restriction and behavioral changes without anti-obesity pharmacotherapy is associated with lower blood pressure.

And yet you should be aware that there is a connection between Duromine and high blood pressure. So, before you start taking the drug, be sure to inform your doctor about having high blood pressure, whether you can control it medically or not. It is necessary to minimize possible risks and help the doctor select the optimal dosage for you.

Duromine and insomnia

Insomnia can begin bothering you either during the use or after the end of the Duromine treatment course, for several days or longer. It usually appears 3-5 days after using the first pill. The methods of sleep disturbance prevention and Duromine insomnia cure include the following:

Taking Duromine as early as possible in the morning
Using sleeping pills
Waiting for insomnia to go away on its own
Stopping to take Duromine for 3-4 days, then resuming (high probability of absence of insomnia when starting again)
Reducing the dosage of the drug

Duromine and insomnia are related, but not everyone has this symptom, so the doctor should determine the optimal dosage and dosing schedule individually.

Duromine, dizziness and nausea

Duromine nausea is undoubtedly one of the most unpleasant symptoms, along with dizziness. The following list contains a couple of recommendations on how to reduce these side effects:

Wait until nausea goes away on its own
Drink more water
Eat enough, avoid starvation
Eat something light when you take the pill

The unwanted adverse reaction should go away as soon as the body adapts to the drug’s action. This usually happens by the end of the first week of the treatment course.


Duromine and constipation

Does Duromine make you constipated? Unfortunately, not everyone dares to discuss this topic in forums with a large audience. Do not be shy; you need to know all possible side effects (including Duromine and diarrhea) to minimize their manifestation and enhance the impact of obesity treatment.

You should know that constipation not only causes discomfort due to bloating, heaviness and pain, it can also interfere with your weight loss. Duromine and constipation solutions include increasing water intake, eating fiber-rich foods, and taking laxatives.

Check out the best methods on Duromine constipation relief on our forum in this thread

Duromine and anxiety

Some side effects are common, and some occur as a reaction to an overdose. Duromine anxiety is an effect that can manifest anxiety, rapid breathing, and increased sweating. If it happens, it is recommended to lower the dose used.

Duromine and periods

Can Duromine affect your period? The manufacturer of Duromine did not indicate menstrual irregularities in the list of possible side effects. If you notice any symptoms, contact your healthcare professional. Duromine side effects in the menstrual cycle are not proven.


Duromine and mental health

Can Duromine make you tired? Yes, but this is usually due to another side effect – insomnia. Duromine is a CNS stimulant; therefore, it affects the functioning of your central nervous system and, thus, can cause various unwanted reactions from the part of this system.

If you notice among Duromine side effects anger while taking this drug, and the problem persists, you should consult with your doctor for previously undiagnosed diseases.

And remember, you are not alone who struggle with mental or mood issues on Duromine.

How long do Duromine side effects last

This question cannot be answered unequivocally since the side effects manifest differently in different people or do not appear at all. Duromine 15 mg side effects or Duromine 40 mg side effects may occur with equal probability if you violate the dosage regimen and the recommendations for the pills’ use.

As for withdrawal syndrome, you shouldn’t worry about it. Most men and women find it easy to stop taking Duromine, as the body is tolerant of the drug over time. This means that you are likely not to feel any Duromine side effects (30 mg or any other dosage) after finishing your weight loss course.

Numerous weight loss success stories with Duromine show that its effectiveness outweighs the discomfort associated with side effects (no matter how long they last) and helps people get thinner and happier. The main thing is to follow the dosing regimen and the doctor’s recommendations.


Our goal is to provide you with the most up-to-date and reliable information. However, medications affect each person differently, so we cannot guarantee that all possible side effects have been listed in the article. 

The information provided does not replace expert advice. Always discuss possible side effects with a doctor who knows your medical history and contact him if you face any adverse reactions.


7 thoughts on “Duromine Side Effects: All You Need to Know”
  1. This drug is really effective, but the side effects are a bit too much for me. I’ve been experiencing anxiety since I started taking Duromine. Has anyone else dealt with this???

    • Hi Judith! Sorry to hear that you’re experiencing anxiety. Duromine can cause some people to feel anxious due to its stimulatory effect on the central nervous system. Remember, it’s always important to discuss any side effects you’re experiencing with your healthcare provider as they may need to adjust your dosage or suggest an alternative treatment. 💜

    • I totally get it, I had a similar experience. But as Ellen suggested, please contact your doctor. It’s important to talk to a professional. Stay strong 💪!

  2. Don’t forget hydration, folks! I’ve been using Duromine and noticed that drinking more water helped me manage some of the side effects.

  3. Very informative article. I was contemplating taking Duromine, but I have high blood pressure. Is it still safe for me to take this medication?

    • It’s crucial to inform your doctor about your high blood pressure before starting Duromine. They may want to monitor your blood pressure more frequently or they might suggest an alternative treatment plan. Always make sure to have these conversations with your healthcare provider first.

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